Abstract Background Recent single-cell transcriptomic studies report that IDH-mutant gliomas share a common hierarchy of cellular phenotypes, independent of genetic subtype.However, the genetic differences between IDH-mutant glioma subtypes are prognostic, predictive of response to chemotherapy, and correlate with distinct tumor microenvironments.R
The objective of this research is to produce high quality of charcoal from the most known local wastes as a binder.The solid waste was collected from Bonga city and the production of charcoal briquette based on different binder preparation.The local wastes like sawdust and paper were used as a binder comparing with starch as a standard binder.Since
BackgroundStudies exploring the impact of receiving end-of-life prognoses in patients with advanced cancer use a variety of different measures to evaluate the outcomes, and thus report often conflicting findings.The standardization of outcomes reported in studies of prognostication in palliative cancer care could enable uniform assessment and repor
Abstract Probing the surface of proteins to predict the binding site and binding affinity for a given small molecule is a critical but challenging task in drug discovery.Blind docking addresses this issue by performing docking on binding regions randomly sampled Wire Cages from the entire protein surface.However, compared with local docking, blind
Abstract Wildlife crime is one of the most profitable illegal industries worldwide.Current actions to reduce it are far from effective and fail to prevent population declines of many endangered species, pressing the need for innovative anti-poaching solutions.Here, we propose and test a poacher early warning system that is based on the movement res